Pathology Nephritis

Pathology nephritis
Macroscopic kidney enlarged, the surface of the slices looked bloated due to swollen.Typical on-medullary border areas kortiko looked pale areas. Histopathological abnormalities, known as 2 different forms of nephrotoxic lesions and lesions of Urinary Tract Infection.

Clinical Manifestation
Acute Type:Heat / subfebris, low back pain uni / bileteralUrinary turbid, sediment examination: leukocytes> 5 cells / PLP, bacteria ()Urine culture: colony growth> 10 ^ 5 ml / urine, arising a few days and disappeared after a series of treatment.
Chronic Type:There are periods of remission / esarsebasi, nyreri dish unlateral / bilateral recurrent-kumatan, can also hot sufebris.Urinary turbid, sediment: leukocytes => 5/plp, bacteria ()Positive urine culture with colony> 10 ^ 5 ml / urine

Management
While awaiting the results of urine culture and sensitivity tests can be given one dose of antibiotics• Nitrofurentoin 3x100 mg• 3x1 nalidixic acid tab• 2x1 pipemedik acid capsuleOr sulfate preparations: combination trimetropim and sulfamethoxazole at a dose of 2x2 tablet. Given between 5-7 days. Following is the results of urine culture and sensitivity tests, give the drugs sensitive to the choice of the first, the drugs are given orally, if possible class of chemotherapeutic. Next new antibiotic options in the first rank.Giving these drugs for 7-10 days.For chronic cases are given maintenance therapy with non-antibiotic drugs: Nitrofurentoin, nalidixic acid, sulfuric acid pipemedik or preparations, given 1 tablet after dinner. Kuur urine cultures performed after the first, and after the maintenance dose given 1 month.